| Title:
|
The Effect of qEEG-Guided Low-Intensity Magnetic Stimulation on Anxiety and Attention Deficit Disorder: A Pre- and Post-Pilot Study
|
| Author(s):
|
1
|
| Subject:
|
Clinical Applications of Brain Mappin
|
|
|
|
Presenter Author:
|
|
| Name:
|
Faezeh Miraboutalebi
|
|
|
|
Author:
|
|
| Name 1:
|
Faezeh Miraboutalebi - Corresponding - Presenter
|
| Affiliation 1:
|
Navid-e-Ayande Zendegi Psychology Clinic
|
|
|
| Name 2:
|
Mahla Noorirad
|
| Affiliation 2:
|
Navid-e-Ayande Zendegi Psychology Clinic
|
|
|
| Name 3:
|
|
| Affiliation 3:
|
|
|
|
| Name 4:
|
|
| Affiliation 4:
|
|
|
|
| Name 5:
|
|
| Affiliation 5:
|
|
|
|
| Name 6:
|
|
| Affiliation 6:
|
|
|
|
| Name 7:
|
|
| Affiliation 7:
|
|
|
|
| Name 8:
|
|
| Affiliation 8:
|
|
|
|
| Name 9:
|
|
| Affiliation 9:
|
|
|
|
| Name 10:
|
|
| Affiliation 10:
|
|
|
|
Abstract
|
Original Research
|
|
introduction :
|
Quantitative EEG (qEEG) enables personalized neuromodulation by identifying cortical regions with abnormal oscillatory activity. Low-intensity magnetic stimulation (Li-TMS) offers a non-invasive approach to regulate brain activity based on qEEG findings. However, quantitative evidence of its effects remains limited. This pilot study investigated the efficacy of qEEG-guided Li-TMS in patients with anxiety, depression, and attention deficit disorder (ADD). The results showed a reduction in brain wave activity in the frontal region. However, due to the small sample size, this reduction was not statistically significant.
|
|
Methods:
|
Fifteen patients (14 with anxiety, 13 with ADD; 12 with comorbid conditions) underwent 19-channel qEEG recording before and after 15–20 sessions of Beta one stimulation (20 min/session, 3 days/week). Stimulation protocols were individualized based on absolute power Z-score abnormalities identified by NeuroGuide. Z-scores for delta, theta, alpha, and beta bands were extracted from frontal regions (Fz, Fp1, Fp2). Paired t-tests were used to compare pre- and post-stimulation Z-scores.
|
|
Results:
|
All frequency bands showed a decreasing trend in Z-scores from pre to post stimulation at frontal sites, suggesting a shift toward normalization of cortical activity. The mean change in alpha Z-score at Fz was −0.215 (SD = 0.412, p = 0.072), approaching statistical significance. Theta power at Fz decreased by a mean of −0.224 (p = 0.215), and beta power at Fz decreased by −0.304 (p = 0.355). Similar non-significant reductions were observed at Fp1 and Fp2 across all bands. No adverse effects were reported.
|
|
Conclusion:
|
qEEG-guided Beta one stimulation demonstrated consistent trends toward reduction in Z-score deviations across frequency bands in patients with anxiety and ADD. The near-significant reduction in alpha power warrants further investigation with larger sample sizes. These preliminary findings support the potential of personalized qEEG-based neuromodulation as a targeted intervention.
|
| Attachment:
|
|
| Keywords:
|
qEEG, Beta one, Low-intensity magnetic stimulation, Anxiety, Attention deficit disorder, Pilot study
|
| Key message:
|
|
| Do you want your abstract to be indexed, if this is selected as one of the top 100
articles?
|
